Tuesday, 5 May 2026

A3 Module 3 – Addison’s Disease (Full Module – A–Z Book Version)

 


(Endocrine / Physical Health Condition)


🧠 What is Addison’s Disease?

Addison’s Disease is a rare, long-term condition where the adrenal glands do not make enough important hormones:

  • Cortisol (stress hormone)
  • Aldosterone (salt and fluid balance hormone)

👉 This usually happens when the immune system mistakenly attacks the adrenal glands (autoimmune disease).


⚙️ What Do the Adrenal Glands Do?

The adrenal glands help the body:

  • Respond to stress
  • Control blood pressure
  • Balance salt and water
  • Maintain energy levels

⚠️ Symptoms of Addison’s Disease

🟡 Long-term (Chronic) Symptoms

  • Severe tiredness (fatigue)
  • Muscle weakness
  • Weight loss
  • Loss of appetite
  • Low blood pressure
  • Darkening of skin (hyperpigmentation)

🔴 Addisonian Crisis (Medical Emergency)

This is a life-threatening sudden episode:

  • Severe stomach, back, or leg pain
  • Vomiting or diarrhoea
  • Severe dehydration
  • Very low blood pressure
  • Confusion or collapse
  • Loss of consciousness

👉 This needs urgent emergency treatment


🧬 Causes of Addison’s Disease

🔹 Most common cause:

  • Autoimmune disease (body attacks adrenal glands)

🔹 Other causes:

  • Tuberculosis (TB)
  • HIV or fungal infections
  • Cancer affecting adrenal glands
  • Bleeding into adrenal glands
  • Surgery removing adrenal glands

🧪 Diagnosis

Doctors may use:

  • Blood tests (cortisol and ACTH levels)
  • Antibody tests (autoimmune markers)
  • CT or MRI scans (to check adrenal glands)

💊 Treatment and Management

✔️ Lifelong treatment is needed:

  • Hydrocortisone (replaces cortisol)
  • Fludrocortisone (replaces aldosterone)

🧠 Key Management Points

  • Medication must be taken every day
  • Doses may increase during illness or stress
  • Never stop medication suddenly

🚨 Stress Dose Rule

During:

  • Illness
  • Surgery
  • Infection
  • Severe stress

👉 Extra medication is needed to prevent crisis


🏥 Medical Safety

People with Addison’s should:

  • Wear a medical alert bracelet or necklace
  • Carry emergency steroid information
  • Inform doctors and schools/workplaces

📊 Prognosis (Outlook)

✔ With treatment:

  • Normal life expectancy
  • Active daily life possible
  • Symptoms controlled

❗ Without treatment:

  • Addisonian crisis can be fatal

🧠 Simple Explanation (Easy Read)

👉 Addison’s disease means:

  • The body does not make enough hormones
  • This makes people feel very tired and weak
  • It can be serious but is treatable

📌 Easy Read Key Points

✔ Rare long-term condition
✔ Affects adrenal glands
✔ Causes tiredness and weight loss
✔ Needs lifelong medication
✔ Can become an emergency if untreated
✔ Most people live normal lives with treatment


🧩 EASY READ SUMMARY BOX

🟦 Addison’s disease is a hormone condition
🟦 It affects energy and blood pressure
🟦 It needs daily medicine
🟦 Emergency treatment may be needed sometimes
🟦 People can live well with support

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A3 Module 3 – Addison’s Disease (Full Module – A–Z Book Version)

  (Endocrine / Physical Health Condition) 🧠 What is Addison’s Disease? Addison’s Disease is a rare, long-term condition where the adr...