Atrial fibrillation (AF or AFib) is a common heart rhythm disorder where the atria (upper chambers of the heart) beat in a rapid, irregular, and uncoordinated way. Instead of contracting properly, they quiver (fibrillate).
It is strongly associated with:
- Increased risk of stroke (4–5 times higher)
- Increased risk of death (about 2 times higher)
- Age-related cardiovascular disease
⚙️ Pathophysiology
In AFib:
- Electrical signals in the atria become chaotic
- Atria lose effective contraction
- This leads to loss of the “atrial kick”
๐ซ Atrial Kick Loss
Normally, atrial contraction adds 20–30% extra blood volume into the ventricles.
When this is lost:
- Cardiac output decreases
- Stroke volume decreases
⚠️ Cardiac Effects
- Blood pools in the atria (stasis)
- Risk of blood clot (thrombus) formation increases
- Clots may travel to the brain → stroke risk
๐ฅ AF with RVR (Rapid Ventricular Response)
- Heart rate >100 bpm (often >150 bpm)
- Can cause dizziness, chest pain, or collapse
๐ ECG Findings
- Irregularly irregular rhythm
- No clear P waves
- Fibrillatory baseline activity
- Variable QRS timing
๐งช Diagnosis
- ECG (primary diagnostic tool)
- Echocardiogram (heart structure check)
-
TEE (Transesophageal Echocardiogram):
- Used to detect clots before cardioversion
-
Risk scoring system:
- CHA₂DS₂-VASc score → estimates stroke risk
๐ Management and Treatment
AFib treatment focuses on 3 main goals:
1. ๐ง Stroke Prevention
-
Anticoagulants:
- Warfarin
- NOACs (e.g. apixaban, rivaroxaban)
2. ❤️ Rate or Rhythm Control
Rate control:
- Slows heart rate without fixing rhythm
Rhythm control:
- Restores normal sinus rhythm
3. ⚡ Procedures
-
Cardioversion
- Synchronized electrical shock (~150 joules)
-
Catheter ablation
- Destroys abnormal electrical pathways
๐ Key Terms
- Arrhythmia: Abnormal heart rhythm
- Atrial kick: Final atrial contraction that fills ventricles
- Thrombus: Blood clot formed inside a vessel or heart
⚠️ Complications
- Stroke (most serious risk)
- Heart failure (reduced output over time)
- Chronic fatigue and reduced exercise tolerance
- Embolic events (clots travelling through bloodstream)
๐ Key Summary
- AFib is a chaotic atrial rhythm disorder
- Leads to poor cardiac efficiency and blood pooling
- Major complication = stroke risk from clot formation
-
Managed with:
- Anticoagulation
- Rate/rhythm control
- Procedures like cardioversion or ablation
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